Pentraxin-3 Levels in Gingival Crevicular Fluid during Canine Retraction with NiTi Coil Spring and Active Tieback

Aim: Orthodontic treatment is routinely carried out in patients with the purpose of correcting various forms of dental malocclusions. Retraction of the canines can be achieved either individually or along with incisor. Pentraxin-3 (PTX-3) is regarded as the true independent indicator of disease activity. Hence, we undertook the present study to assess and compare the level of PTX-3 in patients undergoing canine retraction with active tieback and nickel–titanium (NiTi) coil spring. Materials and methods: The present study included assessment of 25 patients that underwent canine retraction as a part of fixed orthodontic treatment. In the maxillary right and left quadrant, active tieback and NiTi coil spring were used respectively. Gingival crevicular fluid samples were collected 1 hour prior to the commencement of orthodontic canine retraction procedure followed by collection at following time intervals: 1 hour, 1, 7, and 14 days after the start of canine retraction procedure. Enzyme-linked immunosorbent assay kit was used for analysis of the samples as per manufacturer’s instructions. All the data were recorded and compiled. All the results were analyzed by Statistical Package for the Social Sciences software. Results: Nonsignificant difference was observed in the values of PTX-3 at baseline and 1 hour. While comparing the mean Pentraxin-3 Levels in Gingival Crevicular Fluid during Canine Retraction with Nickel–titanium Coil Spring and Active Tieback 1Rakesh Thukral, 2Sukhpreet Mangat, 3Anvesha Ganguly, 4Sanket S Agarkar, 5Harleen Bali, 6Shekhar Grover 1Department of Orthodontics, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India 2Department of Orthodontist, Mumbai, India 3Department of Orthodontist, Kolkata, India 4Department of Orthodontics, Dr. D. Y. Patil Dental College & Hospital, Pune, Maharashtra, India 5Oral Medicine and Radiodiagnosis, Jammu, India 6Department of Community Dentistry, Maulana Azad Dental College & Hospital, New Delhi, India Corresponding Author: Shekhar Grover, Department of Community Dentistry, Maulana Azad Dental College & Hospital, New Delhi, India, Phone: +919501544877, e-mail: [email protected] PTX-3 values between different time intervals in both the study groups, significant difference was observed. Conclusion: In comparison to the active tieback, NiTi coil exhibited faster space closure rate. Clinical significance: In patients undergoing orthodontic treatment, PTX-3 is associated with periodontal remodeling under the effect of orthodontic forces.